Ashburn and Herndon Back Pain Related to Inflammation Reduced with Melatonin
Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to harmful stimuli (injury, pathogens, metabolic stress – a disc herniation compressing a nerve!) as it attempts to restore itself to normal before the harm was done. Poulin Chiropractic of Herndon and Ashburn is always amazed at how the body takes care of itself! Poulin Chiropractic of Herndon and Ashburn sees its Ashburn and Herndon chiropractic care as a partner of the body’s system in healing particularly when spine pain is an issue. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is showing value by interrupting the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.
DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'
Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are associated with intervertebral disc degeneration. (1) IL-1 β actually promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to its cellular level via autophagy, the natural process during which the body’s cells clean out damaged (ie, by inflammation) or unneeded parts. In a new study, melatonin increased autophagy and decreased the degradation of the disc’s extracellular matrix (technically marked by a decrease in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The final conclusion was that melatonin inhibits intervertebral disc degeneration by stimulating autophagy. (3) Wow. Poulin Chiropractic of Herndon and Ashburn is encouraged by this research to see just how well melatonin can work for Ashburn and Herndon back pain linked to disc degeneration.
MELATONIN AND ITS HEALING WAYS FOR THE DISC
Disc degeneration is a very common condition seen at Poulin Chiropractic of Herndon and Ashburn that positive news of melatonin’s benefits are quite rousing. A new study explained how melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Further, melatonin reduced the inflammatory cell collection and decreased the release of associated inflammatory markers IL-1β, IL-6, and TNF-α. With this new finding that melatonin disrupted the IL-1B feedback loop, researchers postulated that melatonin may support the healing process of intervertebral discs after damage has already been done. (1) Poulin Chiropractic of Herndon and Ashburn continues following the new research on the role inflammation performs in Ashburn and Herndon disc degeneration and melatonin’s role in tackling it.
INFLAMMATION AND MELATONIN
The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is growing. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other mechanisms is quite appropriate. It’s also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland produces melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific influence on inflammation and disc degeneration is most attention-getting to Poulin Chiropractic of Herndon and Ashburn and our Ashburn and Herndon back pain patients.
CONTACT Poulin Chiropractic of Herndon and Ashburn
Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management manages disc degeneration for relief of chronic low back pain in her patient.
Schedule your Ashburn and Herndon chiropractic appointment with Poulin Chiropractic of Herndon and Ashburn today. We can talk about the role inflammation plays in your back pain experience and how melatonin may help with the related disc degeneration.
